Translation from well established animal tests into human clinical studies. Test of spatial learning and memory in humans:
- Sensitive for cognitive changes already in early disease stage
- Suitable to detect treatment effects
- Independent from language
- No ceiling effect
- Easy and fast to apply
AMUN - Testing in real version arena
| The development of drugs for dementia has been frustrated by a lack of predictive validity from preclinical to clinical effects. Memory paradigms used with human study participants typically feature tests of episodic verbal memory, paired associative learning or visual recognition Memory.These tasks are very different to the memory paradigms employed in rodents. We have sought to improve the predictive power of preclinical findings by creating a human analogue of the well-known Morris Water Maze. |
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AMUNET- a computer test of spatial memory ability
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