Translation from well established animal tests into human clinical studies. Test of spatial learning and memory in humans:
- Sensitive for cognitive changes already in early disease stage
- Suitable to detect treatment effects
- Independent from language
- No ceiling effect
- Easy and fast to apply
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AMUNET, the computerized test for spatial memory was designed for use with elderly subjects who have no previous computer experience. AMUNET is based on the AMUN real-space tests. Performance on the computer and arena versions of the task are highly correlated. In the AMUNET task the participant is required to move a pointer on the touch-screen or a mouse pointer in a map view of the arena. Currently we offer two versions, one for patients with mild cognitive impairment and very mild dementia, the second one is designed for use in mild to moderate dementia. |
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Memory paradigms used with human study participants typically feature tests of episodic verbal memory, paired associative learning or visual recognition Memory.These tasks are very different to the memory paradigms employed in rodents. We have sought to improve the predictive power of preclinical findings by creating a human analogue of the well-known Morris Water Maze. |
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AMUN- Testing in real version arena |
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